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Mutation-specific therapies in cystic fibrosis - Burkhard Tümmler Mutation-specific therapies in cystic fibrosis - Buch Cystic fibrosis is a severe ion channel disease of autosomal recessive inheritance that is caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene. Thanks to... Mutation-specific therapies in cystic fibrosis - Burkhard Tümmler